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- publication . Article . 2009Open AccessAuthors:Papadopoulos, G. L.; Alexiou, P.; Maragkakis, M.; Reczko, M.; Hatzigeorgiou, A. G.;Persistent IdentifiersPublisher: Oxford University Press (OUP)
Summary: DIANA-mirPath is a web-based computational tool developed to identify molecular pathways potentially altered by the expression of single or multiple microRNAs. The software performs an enrichment analysis of multiple microRNA target genes comparing each set of ...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Open Access EnglishAuthors:Norman E. Davey; M. Madan Babu; Martin Blackledge; Alan Bridge; Salvador Capella-Gutierrez; Zsuzsanna Dosztanyi; Rachel Drysdale; Richard J. Edwards; Arne Elofsson; Isabella C. Felli; ...Publisher: F1000 Research Ltd
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELI...
- publication . Article . 2009Open Access EnglishAuthors:Panagiotis Alexiou; Thanasis Vergoulis; Martin Gleditzsch; George Prekas; Theodore Dalamagas; Molly Megraw; Ivo Grosse; Timos Sellis; Artemis G. Hatzigeorgiou;Persistent IdentifiersPublisher: Oxford University Press
MicroRNAs are small, non-protein coding RNA molecules known to regulate the expression of genes by binding to the 3 0 UTR region of mRNAs. MicroRNAs are produced from longer transcripts which can code for more than one mature miRNAs. miRGen 2.0 is a database that aims t...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . Other literature type . 2021Open AccessAuthors:Spyros Tastsoglou; Dimitrios Zisis; Giorgos Skoufos; Artemis G. Hatzigeorgiou; Marios Miliotis; Ioannis Kavakiotis; Athanasios Alexiou; Eleni C. Gkotsi; Anastasia Lambropoulou; Vasileios Lygnos; ...Persistent Identifiers
pmc: PMC8345031
pmid: 34359584
Publisher: MDPI AGSimple Summary Only recently have the important biomarker capacities of microRNAs (miRNAs) in blood samples during disease been revealed. miRNAs are abundantly detected in circulation, and are less prone to degradation than longer RNA. Details regarding potential discri...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2016Closed AccessAuthors:Vasiliki D. Kostiou; Margarita C. Theodoropoulou; Stavros J. Hamodrakas;Persistent IdentifiersPublisher: Elsevier BV
Heterotrimeric G-proteins form a major protein family, which participates in signal transduction. They are composed of three subunits, Gα, Gβ and Gγ. The Gα subunit is further divided in four distinct families Gs, Gi/o, Gq/11 and G12/13. The goal of this work was to det...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2021Open AccessAuthors:Paraskevi N. Polymenakou; Paraskevi Nomikou; Haris Zafeiropoulos; Manolis Mandalakis; Thekla I. Anastasiou; Stephanos P. Kilias; Nikos C. Kyrpides; Georgios Kotoulas; Antoniοs Magoulas;Persistent Identifiers
doi: 10.3390/en14051414
Publisher: eScholarship, University of CaliforniaCountry: United StatesMarine microbial communities are an untapped reservoir of genetic and metabolic diversity and a valuable source for the discovery of new natural products of biotechnological interest. The newly discovered hydrothermal vent field of Santorini volcanic complex located in ...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . Other literature type . 2015Open Access EnglishAuthors:Huber, Wolfgang; Carey, Vincent J; Gentleman, Robert; Anders, Simon; Carlson, Marc; Carvalho, Benilton S; Bravo, Hector Corrada; Davis, Sean; Gatto, Laurent; Girke, Thomas; ...Persistent IdentifiersCountry: Belgium
Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development of scientific softw...
Exceptional popularityExceptional popularity In top 0.01%Substantial influencePopularity: Citation-based measure reflecting the current impact.Substantial influence In top 1%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. PRED-TAT is a tool that takes a protein sequence as input and discriminating Sec from Tat signal peptides and predicting their cleavage sites.
- publication . Article . 2015Open Access EnglishAuthors:Duarte, Afonso M S; Psomopoulos, Fotis E; Blanchet, Christophe; Bonvin, Alexandre M J J; Corpas, Manuel; Franc, Alain; Jimenez, Rafael C; de Lucas, Jesus M; Nyrönen, Tommi; Sipos, Gergely; ...Persistent IdentifiersPublisher: HAL CCSDCountries: Netherlands, Spain, FranceProject: WT , AKA | ELIXIR - Data for Life Eu... (273655), EC | WENMR (261572), EC | BIOMEDBRIDGES (284209), FCT | EXPL/BBB-BEP/1356/2013 (EXPL/BBB-BEP/1356/2013), FCT | SFRH/BPD/78075/2011 (SFRH/BPD/78075/2011), EC | EGI-INSPIRE (261323)
With the increasingly rapid growth of data in life sciences we are witnessing a major transition in the way research is conducted, from hypothesis-driven studies to data-driven simulations of whole systems. Such approaches necessitate the use of large-scale computationa...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2020Open AccessAuthors:Eva Alloza;Persistent IdentifiersPublisher: Oxford University Press (OUP)Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019 . Embargo End Date: 13 Jan 2020Open Access EnglishAuthors:Davey, Norman E.; Babu, M. Madan; Blackledge, Martin; Bridge, Alan; Capella-Gutierrez, Salvador; Dosztanyi, Zsuzsanna; Drysdale, Rachel; Edwards, Richard J.; Elofsson, Arne; Felli, Isabella C.; ...Persistent IdentifiersPublisher: Apollo - University of Cambridge RepositoryCountries: United Kingdom, Cyprus, Netherlands, Belgium, Spain, United KingdomProject: UKRI | Bioinformatics Resources ... (BB/P024092/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), EC | IDPfun (778247), WT | Protein Data Bank in Euro... (104948)
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELI...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2021Open Access EnglishAuthors:Maria Vasilarou; Nikolaos Alachiotis; Joanna Garefalaki; Apostolos Beloukas; Pavlos Pavlidis;Persistent IdentifiersCountry: Netherlands
Full-genome-sequence computational analyses of the SARS-coronavirus (CoV)-2 genomes allow us to understand the evolutionary events and adaptability mechanisms. We used population genetics analyses on human SARS-CoV-2 genomes available on 2 April 2020 to infer the mutati...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Other literature type . Article . Preprint . 2021 . Embargo End Date: 27 Jan 2022Open Access EnglishAuthors:Walsh I.; Fishman D.; Garcia-Gasulla D.; Titma T.; Pollastri G.; Capriotti E.; Casadio R.; Capella-Gutierrez S.; Cirillo D.; Del Conte A.; ...Persistent Identifiers
handle: 2117/350489
Publisher: Nature ResearchCountries: Spain, Italy, Italy, Italy, BelgiumSupervised machine learning is widely used in biology and deserves more scrutiny. We present a set of community-wide recommendations (DOME) aiming to help establish standards of supervised machine learning validation in biology. Formulated as questions, the DOME recomme...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2014Open AccessAuthors:Panagiotis Moulos; Pantelis Hatzis;Persistent IdentifiersPublisher: Oxford University Press (OUP)
RNA-Seq is gradually becoming the standard tool for transcriptomic expression studies in biological research. Although considerable progress has been recorded in the development of statistical algorithms for the detection of differentially expressed genes using RNA-Seq ...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Authors:Birgit Vogel; Giora Weisz; C. Michael Gibson; Ioannis Iakovou; Annapoorna Kini; Serdar Farhan; Sabato Sorrentino; Michela Faggioni; Antonio Colombo; Philippe Gabriel Steg; ...Persistent IdentifiersPublisher: Georg Thieme Verlag KG
Background Data on geographical variations in dual antiplatelet therapy (DAPT) cessation and the impact on outcomes after percutaneous coronary intervention (PCI) are limited. We sought to evaluate geographical patterns of DAPT cessation and associated outcomes in pati...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2017Open AccessAuthors:John Alexander; Dimitris Mantzaris; Marianthi Georgitsi; Petros Drineas; Peristera Paschou;Persistent IdentifiersPublisher: ZenodoCountry: United KingdomProject: EC | TS-EUROTRAIN (316978), EC | EMTICS (278367)
Background: The increasing volume and complexity of high-throughput genomic data make analysis and prioritization of variants difficult for researchers with limited bioinformatics skills. Variant Ranker allows researchers to rank identified variants and determine the mo...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2016Open AccessAuthors:Lakiotaki, Kleanthi; Kartsaki, Evgenia; Kanterakis, Alexandros; Katsila, Theodora; Patrinos, George P.; Potamias, George;Persistent IdentifiersPublisher: Public Library of Science (PLoS)Project: WT , EC | RD-CONNECT (305444)
One of the challenges that arise from the advent of personal genomics services is to efficiently couple individual data with state of the art Pharmacogenomics (PGx) knowledge. Existing services are limited to either providing static views of PGx variants or applying a s...
Average popularityAverage popularity In bottom 99%Average influencePopularity: Citation-based measure reflecting the current impact.Average influence In bottom 99%Influence: Citation-based measure reflecting the total impact.Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. HMM-TM is a tool that takes a protein sequence as input and predicts the transmembrane regions of alpha-helical
Pattern discovery for microsatellite genome analysis. MiGA is a user friendly programme for the detection of all microsatellite loci in genomic data.
- software . 2017Open Source C#Authors:Moschonas, Nicholas; Klapa, Maria;Publisher: bio.tools
PICKLE (Protein InteraCtion KnowLedgebasE) is a meta-database for the direct protein-protein interactome of the human and the mouse proteomes, integrating publicly available source protein-protein interaction (PPI) databases via genetic information ontology. PICKLE inte...